Alcohol occupies an unusual space in our lives. It’s legal, readily available, and a large part of our social culture. A constant presence at happy hours, parties, holidays, and date nights, it’s a way to relax, unwind, or connect with others, background noise behind the goings-on of the day. But casual imbibing is far removed from the excesses of abuse, and the line between both is remarkably easy to cross. Nearly 29 million people in the U.S. struggled with alcohol use disorder in 2023 — 16.8 million of them men. Thankfully, there are treatment centers like Chapter 5 that can offer medication-assisted treatment options, like Naltrexone for alcoholism in Arizona.
Sometimes, the grip of addiction and alcoholism can be too all-consuming to conquer on one’s own. With the help of interventions like naltrexone for alcoholism, medication for alcohol addiction opens a pathway to recovery that clears away some of the roadblocks that can impede the detox and rehab processes.
Does naltrexone work for alcohol abuse? Is it an effective alcoholism treatment, and when can someone benefit from it? If you, a family member, or a friend seek out treating alcohol use disorder in 2025, keep reading to learn more.
What Is Naltrexone?
Taking drugs or drinking alcohol feeds parts of the brain to produce feel-good chemicals that make you want more and more of the drug, which can eventually lead to alcohol dependency and addiction.
Naltrexone for alcoholism is a drug first made more than 40 years ago primarily to treat opioid withdrawal, but it’s also effective for alcohol use disorder. “Many clinical trials have demonstrated that naltrexone consistently reduces the overall amount of alcohol consumed and the number of heavy drinking days,” notes a 2018 study.
What Does Naltrexone Treat?
Here are the substance use disorders that naltrexone can assist with:
Alcohol Use Disorder
Does naltrexone work for alcohol abuse? If you receive a naltrexone prescription from a doctor, it will come in the brand names ReVia or Vivitrol as either a 50–100mg pill (taken daily) or a 380mg extended-release injectable for opioid use disorder. But is it appropriate for everyone with alcohol use disorder?
“The ideal patient for naltrexone therapy would be a person who has moderate-to-severe alcohol dependence — for example, a person who drinks on more than 50% of days, consumes more than five drinks a day, and has alcohol-related problems,” notes the study “Naltrexone for the Management of Alcohol Dependence.” “Such a person has probably failed in attempts to quit drinking but has a relatively high motivation to be abstinent or at least to try abstinence for a while.”
“Naltrexone is also an ideal medication for those who are looking to moderate their use,” notes the American Journal of Psychiatry. “Moderation is often a goal of treatment for individuals struggling with their alcohol use, and naltrexone can provide a tool for individuals to use as they explore the role of alcohol in their lives.”
Opioid Use Disorder
Naltrexone is also effective in treating opioid use disorder and addictions to drugs such as heroin, fentanyl, morphine, codeine, and others (like opioid prescription medicine).
Naltrexone treatment begins when you have been opioid-free for at least one week to 10 days, reducing both the euphoric and sedative feelings of the drug and opioid cravings.
Due to its effectiveness as a meditation for alcohol addiction and opioid use disorder, naltrexone is ideal for people who suffer from both conditions or mental illness — co-occurring disorders that naltrexone can treat simultaneously after receiving a dual diagnosis.
How Does Naltrexone for Alcoholism in Arizona Work?
Alcohol’s influence on the brain is one of the main drivers of addiction. Actually, the National Institute on Alcohol Abuse and Alcoholism says that alcohol is what is called “dually reinforcing” since it activates your brain’s reward processing system that mediates pleasure while also reducing neurological activity that mitigates negative feelings like stress, anxiety, or emotional pain.
Naltrexone works to target and counteract the effects of this reward system, reducing one’s desire to drink.
According to the Substance Abuse and Mental Health Services Administration (SAMHSA), a naltrexone dose binds itself to the endorphin receptors in your brain, blocking the pleasurable effects of drinking, effectively lowering your desire to drink and reducing cravings.
What Are the Benefits of Naltrexone for Alcohol Abuse?
Naltrexone for alcohol abuse offers the following benefits:
Reduces Cravings for Alcohol
Naltrexone is, in essence, an alcohol anti-craving medicine. Cravings, the strong, compulsive, almost irresistible desire to drink, are one of the chief symptoms of alcoholism that can run the risk of relapse. Two-thirds of people treated for alcohol use disorder relapse and resume drinking within six months, according to studies.
“Naltrexone can reduce your urge or desire to drink and can help you continue to choose not to drink,” notes the U.S. Department of Veterans Affairs. Just like it does with treating opioid abuse, naltrexone for alcohol abuse is effective in minimizing these cravings by binding to your brain’s endorphin receptors to reduce the positive reinforcement that comes from drinking.
Increased Likelihood for Long-Term Sobriety
“Without this positive reinforcement, alcohol cravings may decrease, heavy alcohol use may decrease, and those who have stopped drinking may not return to heavy alcohol use if they start drinking again,” notes the Office of Addiction Services and Supports (OASAS) for New York, touting the benefits of naltrexone as a medication for alcohol addiction.
Research consistently shows that medication-assisted treatment, or MAT for alcohol, plays an integral part in treating alcohol use disorder, not only for reducing cravings but for supporting long-term sobriety, increasing the odds of lasting recovery, especially after rehab has finished. “Once a patient stops drinking, taking naltrexone helps patients maintain their sobriety,” notes SAMHSA.
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Side Effects of Naltrexone for Alcoholism
Most naltrexone treatments as part of a MAT for alcohol plan last about three to four months, notes SAMHSA, and as with any medication, understanding the side effects of naltrexone for alcoholism helps maximize its efficacy. Some side effects may include:
- Nausea
- Sleepiness
- Headaches
- Dizziness
- Vomiting
- Decreased appetite
- Pain and cramps in muscles, joints
Other Medications for Alcohol Abuse
Naltrexone for alcoholism is just one drug used in alcohol use disorder treatment. Including naltrexone, additional drugs are recommended and trusted as medication for alcohol addiction:
Acamprosate
Acamprosate, or its brand name Campral, helps prevent relapses in people who have successfully quit drinking and sought alcohol treatment. It works by mediating the levels of gamma-amino-butyric acid, or GABA, in the brain, which can influence alcohol cravings.
The Mayo Clinic notes that acamprosate is not a cure for alcoholism, but rather, it helps you remain abstinent and sober.
Disulfiram
Disulfiram (brand name Antabuse) is also used as a medication to help you stay away from alcohol after you have stopped drinking completely. How does disulfiram work? It works to block a liver enzyme that breaks down acetaldehyde, an alcohol byproduct, to discourage drinking. “When someone taking disulfiram drinks even a small amount of alcohol, the buildup of acetaldehyde in the blood causes unpleasant symptoms such as flushing, nausea, vomiting, rapid heart rate, and headache,” says the OASAS.
Baclofen
Baclofen is a muscle relaxant often used to treat people suffering from multiple sclerosis. Like acamprosate, baclofen also binds to the brain’s GABA receptors to reduce cravings and increase alcohol abstinence.
The Benefits of Alcohol Abuse Treatment in Arizona
In Prescott, AZ, Royal Life Centers at Chapter 5’s mission is to help men down the road to recovery and overcome substance and drug abuse disorders to live happier, more fulfilling lives.
Some people may wonder why rehab or treatment for alcoholism is necessary when they can quit solo or go cold turkey. While these efforts are admirable and illustrate a desire for positive change, quitting alcohol abruptly can carry severe withdrawal syndromes that are not only difficult to manage but can lead to relapse.
But under the guidance of a rehab and recovery program in Chapter 5, filled with compassion, care, and placing your needs first, you are empowered and equipped with the tools to sever your ties with alcohol, rebuild your life, and redefine yourself.
Naltrexone As Part of an Overall Alcohol Abuse Recovery Plan
Naltrexone for alcoholism is just one component of a comprehensive treatment plan, a supplement to a well-rounded alcohol abuse recovery plan encompassing different therapies and modes of treatment to set you along the path of living clean and sober.
Psychotherapy for Alcohol Addiction in Arizona
With your primary therapist at your side, begin to understand and unlock the nature of your relationship with alcohol and begin to take steps to identify your triggers, develop coping strategies, and build healthier habits. Goal-oriented talk therapies like cognitive behavioral therapy, or CBT, work to help you understand how your thoughts influence your actions when it comes to addiction. Additionally, harness the power of “we” through group therapies that build a network of support with peers with similar goals to conquer addiction.
Holistic Therapy for Alcohol Addiction in Arizona
Holistic therapy is meant for your whole person — body, mind, and spirit. Yoga, mindfulness meditation, and more enable you to tap into the skills you possess within to heal substance abuse dependency, learn to let go of addiction, live in this present moment, and harness a renewed sense of purpose, self, and sobriety.
The first step to stop drinking alcohol begins with you. You don’t need to go it alone. Take that brave step to seek treatment and make getting sober a reality. Change your life with one call, and contact us today. You can do it; we can help.
- Alcohol Use Disorder (AUD) in the United States: Age Groups and Demographic Characteristics | National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Naltrexone: A History and Future Directions – PMC
- AUD-Patient AD-Naltrexone
- What is Naltrexone? Side Effects, Uses, Dose & Risk | SAMHSA
- Vivitrol, ReVia (naltrexone) dosing, indications, interactions, adverse effects, and more
- Naltrexone and Alcohol Use | American Journal of Psychiatry
- Naltrexone for the Management of Alcohol Dependence – PMC
- Neuroscience: The Brain in Addiction and Recovery | National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Alcoholism: Getting the Facts – Department of Mental Health
- AUD-Patient AD-Naltrexone
- Medications for the Treatment of Alcohol Use Disorder | Office of Addiction Services and Supports
- What to know about baclofen and alcohol
- Cognitive Behavioral Therapy (CBT): What It Is & Techniques